Prophage induction of Escherichia coli (lambda) by N-nitrosamines.
نویسندگان
چکیده
Carcinogenic N-nitrosamines were tested for their ability to induce lambda in a lysogenic strain of Escherichia coli K-12 (58-161 F+ Dimethylnitrosamine, di-n-propylnitrosamine, methyl-n-propylnitrosamine, and N-nitrosopiperidine were shown to be inducers of prophage.
منابع مشابه
Prophage induction in lysogenic Escherichia coli with N-nitroso compounds and derivatives.
Prophage induction in lysogenic Escherichia coli W1709 (iota) was determined for 29 N-nitroso compounds, 13 of their denitrosated derivatives, and 7 hydroxylamino and hydrazino analogues of nitrosamines. Minimal inducing concentrations of 0.1 to 2.0 mug/ml were demonstrated for eight nitrosamidines, and concentrations of 0.5 to 25.0 mug/ml were shown for six nitrosamides. Weak inducing activiti...
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عنوان ژورنال:
- Applied microbiology
دوره 29 3 شماره
صفحات -
تاریخ انتشار 1975